Article
Genotype-dependent induction of transmissible chromosomal instability by gamma-radiation and the benzene metabolite hydroquinone.
Cancer research - 1 May 2005
Gowans I Duncan, Lorimore Sally A, McIlrath Joanne M, Wright Eric G
Abstract excerpt
Although it is well established that ionizing radiation and benzene are epidemiologically linked to acute myeloid leukemia (AML), the underlying mechanisms are not understood. We have shown that gamma-radiation can induce a persisting genomic instability in the clonal descendants of hemopoietic s...
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