Article
Differences in invasive capacity of endometrial cancer cell lines expressing different progesterone receptor isotypes: possible involvement of cadherins.
Journal of the Society for Gynecologic Investigation - 1 May 2005
Hanekamp Eline E, Gielen Susanne C J P, De Ruiter Petra E, Chadha-Ajwani Savi, Huikeshoven Frans J, Burger Curt W, Grootegoed J Anton, Blok Leen J
Abstract excerpt
OBJECTIVE: Loss of expression of progesterone receptors (PR) in endometrial cancer is related to a more invasive and metastatic phenotype. In this study we aim to investigate whether selective loss of PRA or PRB affects the invasive capacity of endometrial cancer cells. METHODS: cDNA microarrays were performed to compare gene expression profiles of a set of endometrial cancer sub-cell lines expressing PRA and/or...
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