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Article

Progesterone receptors in endometrial cancer invasion and metastasis: development of a mouse model.

Steroids - 1 Nov 2003

Hanekamp Eline E, Gielen Susanne C J P, van Oosterhoud Susanna A, Burger Curt W, Grootegoed J Anton, Huikeshoven Frans J, Blok Leen J

Abstract excerpt

Progestagens inhibit growth of endometrial cancer cells in vivo and in vitro, and also are reported to inhibit endometrial cancer cell invasion. The progesterone receptor (PR) isotypes PRA and PRB have different transcriptional activity. There are indications that relative over expression of PRB could lead to development of a more invasive phenotype in endometrial cancer. To study the effect of progestagens and...

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Identifiers

PMID: 14667970
DOI: 10.1016/j.steroids.2003.08.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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