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Article

Physiological role of collagen XVIII and endostatin.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2005

Marneros Alexander G, Olsen Bjorn R

Abstract excerpt

Collagen XVIII is a component of basement membranes (BMs) with the structural properties of both a collagen and a proteoglycan. Proteolytic cleavage within its C-terminal domain releases a fragment, endostatin, which has been reported to have anti-angiogenesis effects. Molecular studies demonstrated binding of the endostatin domain to heparan sulfate and to BM components like laminin and perlecan, but the...

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Identifiers

PMID: 15857886
DOI: 10.1096/fj.04-2134rev

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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