Article
TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia.
European journal of human genetics : EJHG - 1 Jul 2005
Mohrschladt Martina F, van der Sman-de Beer Femke, Hofman Maaike K, van der Krabben Marieke, Westendorp Rudi Gj, Smelt August Hm
Abstract excerpt
The effects of TaqI restriction fragment length polymorphism of the CETP gene on the occurrence of cardiovascular disease (CVD) events were investigated in patients with familial hypercholesterolemia (FH). A total of 300 FH patients, of which 116 (39%) had CVD at the start of the study, were treated with statins during a mean period of 8.5 years. The distribution of Taq1B genotypes was 31% B1B1, 49% B1B2, and 20%...
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