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Article

Hypermutable and fluoroquinolone-resistant clinical isolates of Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 May 2005

Trong Hiep N'Guyen, Prunier Anne-Laure, Leclercq Roland

Abstract excerpt

Over 124 methicillin-susceptible Staphylococcus aureus 0/74 fluoroquinolone-susceptible versus 5/50 fluoroquinolone-resistant isolates were hypermutable. Hypermutable isolates combined mutations in gyrA, parC, and/or parE genes. One strain had a large deletion of the mutator mutS and mutL genes. No relevant mutation in mutS and mutL genes was found in the other isolates.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15855537
DOI: 10.1128/AAC.49.5.2098-2101.2005
PMCID: PMC1087674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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