Article
Ras pathway signaling accelerates programmed cell death in the pathogenic fungus Candida albicans.
Proceedings of the National Academy of Sciences of the United States of America - 17 Jan 2006
Phillips Andrew J, Crowe Jonathan D, Ramsdale Mark
Abstract excerpt
A better understanding of the molecular basis of programmed cell death (PCD) in fungi could provide information that is useful in the design of antifungal drugs that combat life-threatening fungal infections. Harsh environmental stresses, such as acetic acid or hydrogen peroxide, have been shown to induce PCD in the pathogenic fungus Candida albicans. In this study, we show that dying cells progress from an...
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