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Article

T wave morphology analysis distinguishes between KvLQT1 and HERG mutations in long QT syndrome.

Heart rhythm - 1 Sept 2004

Kanters Jørgen K, Fanoe Søren, Larsen Lars A, Bloch Thomsen Poul Erik, Toft Egon, Christiansen Michael

Abstract excerpt

OBJECTIVES: The aim of this study was to develop an objective method to distinguish between HERG and KvLQT1 genotypes on the surface ECG. BACKGROUND: The two most prevalent genes affected in long QT syndrome (LQTS) are KvLQT1 (KCNQ1) and HERG (KCNH2), which are mutated in >90% of patients with a reported LQTS genotype. It is known that T waves have lower amplitude and more notches in HERG patients than T waves in...

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Source

Identifiers

PMID: 15851171
DOI: 10.1016/j.hrthm.2004.05.002

Genes

KCNH2
KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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