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Article

Influence of RNA structural stability on the RNA chaperone activity of the Escherichia coli protein StpA.

Nucleic acids research - 1 Jan 2005

Grossberger Rupert, Mayer Oliver, Waldsich Christina, Semrad Katharina, Urschitz Sandra, Schroeder Renée

Abstract excerpt

Proteins with RNA chaperone activity are able to promote folding of RNA molecules by loosening their structure. This RNA unfolding activity is beneficial when resolving misfolded RNA conformations, but could be detrimental to RNAs with low thermodynamic stability. In order to test this idea, we constructed various RNAs with different structural stabilities derived from the thymidylate synthase (td) group I intron...

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Identifiers

PMID: 15849314
DOI: 10.1093/nar/gki515
PMCID: PMC1084320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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