Article
Drug resistance and antiretroviral drug development.
The Journal of antimicrobial chemotherapy - 1 Jun 2005
Shafer Robert W, Schapiro Jonathan M
Abstract excerpt
As more drugs for treating HIV have become available, drug resistance profiles within antiretroviral drug classes have become increasingly important for researchers developing new drugs and for clinicians integrating new drugs into their clinical practice. In vitro passage experiments and comprehensive phenotypic susceptibility testing are used for the pre-clinical evaluation of drug resistance. Clinical studies...
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