Article
Clinical use of genotypic and phenotypic drug resistance testing to monitor antiretroviral chemotherapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Mar 2001
Hanna G J, D'Aquila R T
Abstract excerpt
Assays that detect antiretroviral drug resistance in human immunodeficiency virus have recently become available to clinicians. Phenotypic assays measure the drug susceptibility of the virus by determining the concentration of drug that inhibits viral replication in tissue culture. Genotypic assays determine the presence of mutations that are known to confer decreased drug susceptibility. Although each type of...
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