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The effect of cyclin D1 (CCND1) G870A-polymorphism on breast cancer risk is modified by oxidative stress among Chinese women in Singapore.

Carcinogenesis - 1 Aug 2005

Ceschi Michela, Sun Can-Lan, Van Den Berg David, Koh Woon-Puay, Yu Mimi C, Probst-Hensch Nicole

Abstract excerpt

Cyclin D1 (CCND1), an intracellular cell-cycle regulatory protein with checkpoint function, can promote cell proliferation or induce growth arrest and apoptosis depending on the cellular context. We hypothesized that the direction of the association between the (CCND1) G870A-polymorphism and brea...

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Source

Identifiers

PMID: 15845652
DOI: 10.1093/carcin/bgi093

Genes

CCND1
GSTM1
GSTT1
GSTP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15845652-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The effect of cyclin D1 (CCND1) G870A-polymorphism on breast cancer risk is modified by oxidative stress among Chinese women in Singapore.PMID 15845652Read ↗

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Association of cyclin D1 genotype with breast cancer risk and survival.Semantic proximity Read ↗

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Cyclin D1 Pro241Pro (CCND1-G870A) polymorphism is associated with increased cancer risk in human populations: a meta-analysis.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls.Semantic proximity Read ↗

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