Article
[Association of p53 gene polymorphism with susceptibility to ovarian cancer].
Zhonghua fu chan ke za zhi - 1 Nov 2004
Kang Shan, Duan Li-Hong, Zhang Jian-Hui, Guo Wei, Wang Na, Li Yan
Abstract excerpt
OBJECTIVE: To investigate the association of p53 codon 72 and p53 intron 3 (PIN3) polymorphism with susceptibility to epithelial ovarian cancer in northern Chinese women. METHODS: p53 codon 72 and PIN3 genotyping was performed by DNA fragments with sequence specific primers among 124 patients with ovarian cancer and 128 healthy control women. RESULTS: The frequency of the Pro and Arg allele among ovarian cancer...
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