Article
Allele-specific transcript quantification detects haplotypic variation in the levels of the SDF-1 transcripts.
Human molecular genetics - 15 Jun 2005
Kimura Ryosuke, Nishioka Tomoki, Soemantri Augustinus, Ishida Takafumi
Abstract excerpt
It has been suggested that SDF1-G801A, a single nucleotide polymorphism (SNP) in the 3' untranslated region (UTR) of the SDF1 gene, is associated with susceptibility to diseases such as AIDS and type-I diabetes. However, experimental studies examining the effect of SDF1-G801A on SDF-1 expression have not supported its functional importance. In this study, to examine whether other polymorphisms have a cis-acting...
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