Article
Impact of apolipoprotein A5 polymorphisms on insulin sensitivity and beta-cell function.
Pancreas - 1 May 2005
Chiu Ken C, Chiu Yen-Feng, Boyadjian Avetis Arthur, Fernando Sandra, Kwan Connie, Chuang Lee-Ming
Abstract excerpt
OBJECTIVES: Alternation in lipid metabolism can affect both insulin sensitivity and beta-cell function. Apolipoprotein A5 (APOA5) is an important determinant of lipid metabolism. The impact of the APOA5 gene on insulin sensitivity and beta-cell function has not been examined. METHODS: We examined the influence of 2 amino acid polymorphisms (V150M and G182C) in the APOA5 gene on insulin sensitivity and beta-cell...
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