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CYP19A1 (aromatase) dominates female gonadal differentiation in chicken ( <i>Gallus gallus</i> ) embryos sexual differentiation

29 Sept 2020

Abstract excerpt

Cytochrome P450 Family 19 SubFamily A member 1 (CYP19A1) gene encodes an aromatase which regulates the sexual differentiation in vertebrates by initiating and maintaining 17β-Estradiol (E2) synthesis. Here, we described the spatiotemporal expression pattern of CYP19A1 and its functional role in the embryonic gonad development in amphoteric chickens (Gallus gallus). Results showed that CYP19A1 exhibited a sexually...

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PMID: 32990306
DOI: 10.1042/bsr20201576

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