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Article

Size polymorphisms due to changes in the number of O-glycosylated tandem repeats in the Dictyostelium discoideum glycoprotein PsA.

Genetics - 1 Apr 1992

Gooley A A, Marshchalek R, Williams K L

Abstract excerpt

The molecular weight polymorphism in the Dictyostelium discoideum cell surface glycoprotein PsA is due to incremental copies of an O-glycosylated tandem tetrapeptide repeat. Allelic variation at the pspA locus results in a PsA glycoprotein with three, four or five tandem copies of Pro-Thr-Val-Thr. The simplest explanation for the origin of this polymorphism is an unequal crossing over event in the ancestral gene...

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Identifiers

PMID: 1582556
DOI: 10.1093/genetics/130.4.749
PMCID: PMC1204926

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