Article
Amino acid repeats cause extraordinary coding sequence variation in the social amoeba Dictyostelium discoideum.
PloS one - 1 Jan 2012
Scala Clea, Tian Xiangjun, Mehdiabadi Natasha J, Smith Margaret H, Saxer Gerda, Stephens Katie, Buzombo Prince, Strassmann Joan E, Queller David C
Abstract excerpt
Protein sequences are normally the most conserved elements of genomes owing to purifying selection to maintain their functions. We document an extraordinary amount of within-species protein sequence variation in the model eukaryote Dictyostelium discoideum stemming from triplet DNA repeats coding for long strings of single amino acids. D. discoideum has a very large number of such strings, many of which are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.