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Article

The prevalence of PIS and PIZ SERPINA1 alleles in healthy individuals and COPD patients in Saudi Arabia: A case-control study.

Medicine - 1 Oct 2017

Al-Jameil Noura, Hassan Amina A, Hassanato Rana, Isac Sree R, Otaiby Maram Al, Al-Shareef Fadwa, Al-Maarik Basmah, Ajeyan Iman Al, Al-Bahloul Khloud, Ghani Samina, Al-Torbak Dana

Abstract excerpt

Alpha-1 antitrypsin (AAT) is an acute phase protein produced in hepatocytes. Its deficiency affects the lungs and liver. A case-control study was carried out to determine the prevalence of 2 common deficiency alleles, PI*S and PI*Z, for alpha-1 antitrypsin deficiency (AATD) in both healthy and chronic obstructive pulmmonary disease (COPD)-affected Saudi populations and to clarify the importance of genetic tests...

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Source

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Identifiers

PMID: 29049242
DOI: 10.1097/MD.0000000000008320
PMCID: PMC5662408

Genes

SERPINA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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