Article
[The investigation of genotype and expression of alpha1-AT in patients with COPD].
Zhonghua yi xue za zhi - 18 May 2005
Zhang Yan, He Bei, Zhao Ming-wu, Wang Xiao-hong, Jiang Ling, Yao Wan-zhen
Abstract excerpt
OBJECTIVE: To detect genotype and expression of alpha1-AT in the patients with COPD to investigate the effect of alpha1-AT on pathogenesis of COPD. METHODS: Detection of PiZ allele in exon V and S allele in exon III were performed by PCR-Amplification of Specific Allele (PASA). The levels of serum alpha1-AT in some of subjects were measured by Enzyme-Linked Immunoadsordent Assay (ELISA). RESULTS: The PCR...
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