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Article

Effect of 5-haplotype of dysbindin gene (DTNBP1) polymorphisms for the susceptibility to bipolar I disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2007

Pae Chi-Un, Serretti Alessandro, Mandelli Laura, Yu Hye-Sook, Patkar Ashwin A, Lee Chang-Uk, Lee Soo-Jung, Jun Tae-Youn, Lee Chul, Paik In-Ho, Kim Jung-Jin

Abstract excerpt

We investigated a possible association between dysbindin gene (DTNBP1) variants and bipolar I disorder (BID). Five SNPs within DTNBP1 (rs3213207, rs1011313, rs2005976, rs760761, and rs2619522) were genotyped for 151 patients with BID and 478 controls. We observed a significant protective association of the haplotype A-C-G-T-A (all SNPs, P = 0.00016) and particularly G-T-A (the last three SNP, P = 0.00007) within...

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Source

Identifiers

PMID: 17192893
DOI: 10.1002/ajmg.b.30439

Genes

DTNBP1
BID

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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