Article
Programmed cell death 1 gene polymorphisms is associated with ankylosing spondylitis in Chinese Han population.
Rheumatology international - 1 Feb 2011
Liu Xiang, Hu Li-Hua, Li Yi-Rong, Chen Feng-Hua, Ning Yong, Yao Qun-Feng
Abstract excerpt
Programmed cell death 1 (PD-1) has been reported to have a genetic association in several autoimmune diseases. The aim of this study was to investigate the association of PD-1 polymorphisms and haplotypes with ankylosing spondylitis (AS) in Chinese Han population. In a case-control association study, three single-nucleotide polymorphisms (SNP), PD-1.3 G/A, PD-1.5 C/T and PD-1.9 T/C, were genotyped in 216 AS...
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