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Article

Silencing of Fshr occurs through a conserved, hypersensitive site in the first intron.

Molecular endocrinology (Baltimore, Md.) - 1 Aug 2005

Hermann Brian P, Heckert Leslie L

Abstract excerpt

Expression of the FSH receptor (Fshr) is restricted to testicular Sertoli cells and ovarian granulosa cells, thereby limiting the direct targets of FSH action to these somatic cells of the gonads. Earlier studies indicate that transcription of Fshr in the gonads requires elements outside the gene's immediate 5' flanking sequence. To help uncover candidate regulatory sequences, comparative genomics and...

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Identifiers

PMID: 15817654
DOI: 10.1210/me.2004-0244
PMCID: PMC1547732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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