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Article

Endo180 binds to the C-terminal region of type I collagen.

The Journal of biological chemistry - 17 Jun 2005

Thomas Emily K, Nakamura Misa, Wienke Dirk, Isacke Clare M, Pozzi Ambra, Liang Peng

Abstract excerpt

Type I collagen is a fibril-forming heterotrimer composed of two alpha1 and one alpha2 chains and plays a crucial role in cell-matrix adhesion and cell differentiation. Through a comprehensive differential display screening of oncogenic ras target genes, we have shown that the alpha1 chain of type I collagen (col1a1) is markedly down-regulated by the ras oncogene through the mitogen-activated protein kinase...

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Identifiers

PMID: 15817460
DOI: 10.1074/jbc.M501155200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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