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Article

Genome-wide expression profiling of the response to ciclopirox olamine in Candida albicans.

The Journal of antimicrobial chemotherapy - 1 May 2005

Lee Robin E B, Liu Teresa T, Barker Katherine S, Lee Richard E, Rogers P David

Abstract excerpt

OBJECTIVES: The aim of this study was to identify changes in the gene expression profile of Candida albicans upon exposure to the hydroxypyridone anti-infective agent ciclopirox olamine in an effort to better understand its mechanism of action. METHODS: C. albicans SC5314 was exposed to either medium alone or ciclopirox olamine at a concentration equivalent to the IC50 (0.24 mg/L) for 3 h. RNA was isolated and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15814599
DOI: 10.1093/jac/dki105

Genes

CDR2
SIT1
SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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