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Article

Proopiomelanocortin gene variants are associated with serum leptin and body fat in a normal female population.

European journal of human genetics : EJHG - 1 Jun 2005

Chen Yuanneng, Snieder Harold, Wang Xiaoling, Kaviya Bhavini, McCaffrey Clare, Spector Tim D, Carter Nicholas D, O'Dell Sandra D

Abstract excerpt

A major quantitative trait locus (QTL) determining leptin levels has been linked to the proopiomelanocortin (POMC) region on chromosome 2. Most studies, based on under 350 lean or obese subjects, have shown no association between POMC SNP 8246 C/T and serum leptin, but significant associations have been reported with RsaI 8246 C/T SNP haplotypes. We have investigated association of four POMC SNPs with body...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15812563
DOI: 10.1038/sj.ejhg.5201407

Genes

POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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