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Article

Transactivation properties of wild-type and mutant androgen receptors in transiently transfected primary human fibroblasts.

Hormone research - 1 Jan 2005

Holterhus P M, Salzburg J, Werner R, Hiort O

Abstract excerpt

BACKGROUND: Stromal cells play key roles during androgen-mediated male sexual differentiation. Our objective was to establish a transient transfection method for primary human fibroblasts enabling functional characterization of wild-type (wt) and mutant androgen receptor (AR) plasmid constructs, corresponding to partial and complete androgen insensitivity syndrome (PAIS/CAIS). METHODS: An AR-negative fibroblast...

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Identifiers

PMID: 15812177
DOI: 10.1159/000085005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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