Article
Trafficking of androgen receptor mutants fused to green fluorescent protein: a new investigation of partial androgen insensitivity syndrome.
The Journal of clinical endocrinology and metabolism - 1 Oct 1998
Georget V, Térouanne B, Lumbroso S, Nicolas J C, Sultan C
Abstract excerpt
The naturally occurring mutations of the androgen receptor (AR), detected in patients with androgen insensitivity syndrome (AIS), are currently analyzed by in vitro assays. Unfortunately, these assays do not always permit the demonstration of a direct relationship between the in vitro activity of...
Topics
- Androgens
- Cell Line, Transformed
- Drug Resistance
- Green Fluorescent Proteins
- Humans
- Intracellular Membranes
- Luminescent Proteins
- Mutation
- Receptors, Androgen
- Recombinant Fusion Proteins
- Syndrome
- Transcription, Genetic