Article
Characterization of a new allele of Ames waltzer generated by ENU mutagenesis.
Hearing research - 1 Apr 2005
Washington Jesse L, Pitts Darrell, Wright Charles G, Erway L C, Davis Rickie R, Alagramam Kumar
Abstract excerpt
Mutation in the protocadherin 15 (Pcdh15) gene causes hair cell dysfunction and is associated with abnormal stereocilia development. We have characterized the first allele (Pcdh15(av-nmf19)) of Ames waltzer (av) obtained by N-ethyl-N-nitrosourea (ENU) mutagenesis. Pcdh15(av-nmf19) was generated in the Neuroscience Mutagenesis Facility (NMF) at The Jackson Lab (Bar Habor, USA). Pcdh15(av-nmf19) mutants display...
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