Article
An integrated microfluidic system for diagnosis of the resistance of Helicobacter pylori to quinolone-based antibiotics.
Biosensors & bioelectronics - 15 Apr 2016
Chao Chih-Yu, Wang Chih-Hung, Che Yu-Jui, Kao Cheng-Yen, Wu Jiunn-Jong, Lee Gwo-Bin
Abstract excerpt
Helicobacter pylori (H. pylori) is a species of bacteria that can colonize the human stomach mucosa. It is closely associated with gastric diseases such as ulcer and inflammation. Recently, some H. pylori strains were found to express resistance to a family of antibiotics known as quinolones due to single-point mutations. Although traditional polymerase chain reaction (PCR) and molecular diagnostic-based...
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