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The analysis of telomere length and telomerase activity in cloned pigs and cows

1 Apr 2005

Abstract excerpt

Inefficiency in the production of cloned animals is most likely due to epigenetic reprogramming errors after somatic cell nuclear transfer (SCNT). In order to investigate whether nuclear reprogramming restores cellular age of donor cells after SCNT, we measured telomere length and telomerase activity in cloned pigs and cattle. In normal pigs and cattle, the mean telomere length was decreased with biological...

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PMID: 15806556
DOI: 10.1002/mrd.20279

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