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Article

Characterization of lymphoblast mitochondria from patients with Barth syndrome.

Laboratory investigation; a journal of technical methods and pathology - 1 Jun 2005

Xu Yang, Sutachan John J, Plesken Heide, Kelley Richard I, Schlame Michael

Abstract excerpt

Barth syndrome (BTHS) is a multisystem disorder of individuals who carry mutations in tafazzin, a putative phospholipid acyltransferase. We investigated the hypothesis that BTHS is caused by specific impairment of the mitochondrial lipid metabolism. The fatty acid composition of all major mitochondrial phospholipids, phosphatidylcholine (PC), phosphatidylethanolamine (PE), and cardiolipin (CL), changed in...

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Identifiers

PMID: 15806137
DOI: 10.1038/labinvest.3700274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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