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Article

Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties.

Journal of lipid research - 1 Jun 2005

Zhu Xuewei, Wu Gang, Zeng Wuwei, Xue Hong, Chen Baosheng

Abstract excerpt

Apolipoprotein A-I(Milano) (A-I(M)) (R173C), a natural mutant of human apolipoprotein A-I (apoA-I), and five other cysteine variants of apoA-I at residues 52 (S52C), 74 (N74C), 107 (K107C), 129 (G129C), and 195 (K195C) were generated. Cysteine residues were incorporated in each of the various helices at the same helical wheel position as for the substitution in A-I(M). The secondary structural properties of the...

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Identifiers

PMID: 15805548
DOI: 10.1194/jlr.M400401-JLR200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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