Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 Extrachromosomal 2-LTR Circular DNA Is Long-Lived in Human Macrophages

1 Mar 2005

Abstract excerpt

HIV-1 extrachromosomal 2-LTR circles (cc2LTR) are rapidly lost in dividing cell populations and, therefore, might be interpreted as representing new infection and ongoing viral replication. However, recent work demonstrated that cc2LTR persist in infected, growth-arrested T cell lines beyond their predicted half-life as previously determined in dividing cell populations. In this study, the evaluation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15802963
DOI: 10.1089/vim.2005.18.190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 Extrachromosomal 2-LTR Circular DNA Is Long-Lived in Human MacrophagesPMID 15802963Read ↗

Intrinsic Stability of Episomal Circles Formed during Human Immunodeficiency Virus Type 1 ReplicationSemantic proximity Read ↗

Human Immunodeficiency Virus cDNA Metabolism: Notable Stability of Two-Long Terminal Repeat CirclesSemantic proximity Read ↗

Episomal HIV-1 DNA and its relationship to other markers of HIV-1 persistenceSemantic proximity Read ↗

HIV 2-long terminal repeat circular DNA is stable in primary CD4+T CellsSemantic proximity Read ↗

Human macrophages support persistent transcription from unintegrated HIV-1 DNASemantic proximity Read ↗

Evidence for Gene Expression by Unintegrated Human Immunodeficiency Virus Type 1 DNA SpeciesSemantic proximity Read ↗

Unintegrated circular HIV-1 DNA in the peripheral mononuclear cells of HIV-1-infected subjects: association with high levels of plasma HIV-1 RNA, rapid decline in CD4 count, and clinical progression to AIDS.Semantic proximity Read ↗

HIV-1 Protein Expression from Synthetic Circles of DNA Mimicking the Extrachromosomal Forms of Viral DNASemantic proximity Read ↗

Longitudinal monitoring of 2-long terminal repeat circles in peripheral blood mononuclear cells from patients with chronic HIV-1 infectionSemantic proximity Read ↗

Dynamics of Simian Immunodeficiency Virus Two-Long-Terminal-Repeat Circles in the Presence and Absence of CD8+CellsSemantic proximity Read ↗

De novo generation of cells within human nurse macrophages and consequences following HIV-1 infection.Semantic proximity Read ↗

Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integrationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.