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Protection from cytomegalovirus after transplantation is correlated with immediate early 1–specific CD8 T cells

28 Mar 2005

Abstract excerpt

T cells are crucial for the control of cytomegalovirus (CMV) in infected individuals. Although CMV-specific T cells can be quantified by various methods, clear correlates of protection from CMV disease have not been defined. However, responses to the pp65 protein are believed to play an important role. Here, the proportions of interferon gamma-producing T cells following ex vivo activation with pools of...

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PMID: 15795239
DOI: 10.1084/jem.20042384

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