Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.

doi:10.2337/diabetes.54.4.1171

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Article

Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.

Diabetes - 1 Apr 2005

Shimazaki Atsuyuki, Kawamura Yoshihiro, Kanazawa Akio, Sekine Akihiro, Saito Susumu, Tsunoda Tatsuhiko, Koya Daisuke, Babazono Tetsuya, Tanaka Yasushi, Matsuda Masafumi, Kawai Koichi, Iiizumi Tomohiro, Imanishi Masahito, Shinosaki Toshihiro, Yanagimoto Toru, Ikeda Minoru, Omachi Shigeki, Kashiwagi Atsunori, Kaku Kohei, Iwamoto Yasuhiko, Kawamori Ryuzou, Kikkawa Ryuichi, Nakajima Masatoshi, Nakamura Yusuke, Maeda Shiro

Abstract excerpt

To search for a gene(s) conferring susceptibility to diabetic nephropathy (DN), we genotyped over 80,000 gene-based single nucleotide polymorphisms (SNPs) in Japanese patients and identified that the engulfment and cell motility 1 gene (ELMO1) was a likely candidate for conferring susceptibility to DN, in view of the significant association of an SNP in this gene with the disease (intron 18+9170, GG vs. GA+AA,...

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Identifiers

PMID: 15793258
DOI: 10.2337/diabetes.54.4.1171

Genes

ELMO1

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Related research

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Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.PMID 15793258Read ↗

Association of ELMO1 gene polymorphisms with diabetic nephropathy in Chinese population.Semantic proximity Read ↗

Association between ELMO1 gene polymorphisms and diabetic nephropathy in an Iranian populationSemantic proximity Read ↗

Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.Semantic proximity Read ↗

Association of ELMO1 gene polymorphism and diabetic nephropathy among Egyptian patients with type 2 diabetes mellitus.Semantic proximity Read ↗

Association of Genetic Variants of ELMO1 Gene With Diabetic Nephropathy in the North Indian PopulationSemantic proximity Read ↗

ELMO1 variants and susceptibility to diabetic nephropathy in American Indians.Semantic proximity Read ↗

High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy.Semantic proximity Read ↗

Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans.Semantic proximity Read ↗

Association of the ELMO1 gene (snp rs1345365) with development of type 2 diabetes mellitus in the Mexican mestizo population.Semantic proximity Read ↗

Association between ELMO1 gene polymorphisms and diabetic kidney disease: A systematic review and meta-analysis.Semantic proximity Read ↗

Association of single nucleotide polymorphism (rs741301) of the ELMO1 gene with diabetic kidney disease in Polish patients with type 2 diabetes: a pilot study.Semantic proximity Read ↗

Gender differences in the association of ELMO1 genetic variants with type 2 diabetes in Tunisian Arabs.Semantic proximity Read ↗

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