Article
Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.
Diabetes - 1 Nov 2009
Pezzolesi Marcus G, Katavetin Pisut, Kure Masahiko, Poznik G David, Skupien Jan, Mychaleckyj Josyf C, Rich Stephen S, Warram James H, Krolewski Andrzej S
Abstract excerpt
OBJECTIVE: To examine the association between single nucleotide polymorphisms (SNPs) in the engulfment and cell motility 1 (ELMO1) gene, a locus previously shown to be associated with diabetic nephropathy in two ethnically distinct type 2 diabetic populations, and the risk of nephropathy in type 1 diabetes. RESEARCH DESIGN AND METHODS: Genotypic data from a genome-wide association scan (GWAS) of the Genetics of...
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