Article
Molecular analysis of the myocilin gene in Chinese subjects with chronic primary-angle closure glaucoma.
Investigative ophthalmology & visual science - 1 Apr 2005
Aung Tin, Yong Victor H K, Chew Paul T K, Seah Steve K L, Gazzard Gus, Foster Paul J, Vithana Eranga N
Abstract excerpt
PURPOSE: Mutations in the myocilin (MYOC) gene have been implicated in juvenile as well as late-onset primary open-angle glaucoma (POAG). Overall, MYOC mutations account for 3% to 5% of cases of POAG worldwide, making it the most significant gene identified so far in glaucoma. Although there are some similarities in the phenotype of POAG and in particular chronic primary angle-closure glaucoma (PACG), little is...
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