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Article

Two novel myocilin mutations in a Chinese family with primary open-angle glaucoma.

Molecular vision - 5 Sept 2008

Xie Xiaobing, Zhou Xin, Qu Xiying, Wen Jing, Tian Yanli, Zheng Fang

Abstract excerpt

PURPOSE: To investigate the genetic linkage of primary open-angle glaucoma (POAG) in a Chinese family. METHODS: We have screened for myocilin (MYOC) gene mutations in a glaucoma family of five generations. There are fifty-six members of whom 11 were confirmed to have POAG , two with ocular hypertension were considered as POAG suspect, and the remaining 43 were asymptomatic. We also recruited 200 unrelated healthy...

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Source

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Identifiers

PMID: 18776955
PMCID: PMC2530518

Genes

MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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