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Article

New mutation in the MYOC gene and its association with primary open-angle glaucoma in a Chinese family.

Molecular biology reports - 1 Jan 2010

Qu Xiying, Zhou Xin, Zhou Keyuan, Xie Xiaobin, Tian Yanli

Abstract excerpt

Myocilin (MYOC) gene is expressed in many ocular tissues, including the trabecular meshwork, a specialized eye tissue essential in regulating intraocular pressure. Many mutations in MYOC have been detected in primary open-angle glaucoma (POAG). We investigated whether MYOC mutations contributed to the susceptibility to POAG in a Chinese family. In a four-generation family affected with POAG, ocular examinations...

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Source

Identifiers

PMID: 19688280
DOI: 10.1007/s11033-009-9667-3

Genes

MYOC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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