Article
Clinical and genetic evaluation of 8 Polish families with levodopa-responsive parkinsonism.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2005
Krygowska-Wajs A, Kachergus J M, Hulihan M M, Farrer M J, Searcy J A, Booij J, Berendse H W, Wolters E Ch, Wszolek Z K
Abstract excerpt
We studied 8 large Polish families with parkinsonism, 6 of which were newly identified. Thirty-six family members had well-documented levodopa-responsive parkinsonism. The phenotype of affected individuals was indistinguishable from that of persons with idiopathic Parkinson disease (PD). The pattern of inheritance in 5 families was consistent with autosomal dominant transmission; in 3 families the mode of...
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