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Article

Relationship of eNOS gene variants to diseases that have in common an endothelial cell dysfunction.

Journal of cellular and molecular medicine - 1 Jan 2000

Heltianu Constantina, Costache Gabriela, Gafencu Anca, Diaconu Miheala, Bodeanu Mihaela, Cristea Carmen, Azibi K, Poenaru Livia, Simionescu Maya

Abstract excerpt

The endothelial cell (EC) dysfunction is a common characteristic of various pathologies that include atherosclerosis, hypertension, and Fabry's disease. Aware of the role of eNO and ACE in EC dysfunction, we questioned whether polymorphism of eNOS and/or ACE gene may be a common denominator in these pathologies. Patients with CHD (108), HT (109), Fabry's disease (37) and healthy subjects (control, 141) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15784171
DOI: 10.1111/j.1582-4934.2005.tb00343.x
PMCID: PMC6741296

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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