Article
Comparisons of the laccase gene among serotypes and melanin-deficient variants of Cryptococcus neoformans.
Microbiology and immunology - 1 Jan 2005
Tanaka Eiichiro, Ito-Kuwa Shoko, Nakamura Kenjirou, Aoki Shigeji, Vidotto Valerio, Ito Masaaki
Abstract excerpt
Cryptococcus neoformans is a fungus causing life-threatening infections in immunocompromised hosts. Melanin production is a major virulence factor of this fungus and the initial steps of dihydroxyphenylalanine (DOPA)-melanin biosynthesis pathways are catalyzed by laccase. To understand phylogenetic relationships among serotypes of three varieties, partial sequences (about 600 bases) of the laccase gene (CNLAC1)...
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