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Article

Intraspecific variation in fem-3 and tra-2, two rapidly coevolving nematode sex-determining genes.

Gene - 11 Apr 2005

Haag Eric S, Ackerman Amanda D

Abstract excerpt

The sex determination gene fem-3 encodes one of the most divergent proteins yet described in the terrestrial nematode Caenorhabditis. Despite this rapid sequence change, however, FEM-3 is essential for male development in the three species surveyed thus far. It also participates in conserved protein-protein complexes with the transmembrane receptor TRA-2 and the phosphatase FEM-2 in these species. These...

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Identifiers

PMID: 15780968
DOI: 10.1016/j.gene.2004.12.051

Genes

TRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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