Article
Evaluation of microsatellite markers in association studies: a search for an immune-related susceptibility gene in sarcoidosis.
Immunogenetics - 1 Mar 2005
Tanaka Goh, Matsushita Ikumi, Ohashi Jun, Tsuchiya Naoyuki, Ikushima Soichiro, Oritsu Masaru, Hijikata Minako, Nagata Taiji, Yamamoto Kazuhiko, Tokunaga Katsushi, Keicho Naoto
Abstract excerpt
Association studies using linkage disequilibrium (LD) between candidate loci and nearby markers have been proposed to identify susceptibility genes for complex diseases. We analyzed polymorphisms of microsatellites (MSs) and LD patterns of the regions in which candidate genes related to the Th1 immune response have been annotated and attempted to identify a susceptibility gene for sarcoidosis in a marker-based...
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