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Article

Sequential analysis of tacrolimus dosing in adult lung transplant patients with ABCB1 haplotypes.

Journal of clinical pharmacology - 1 Apr 2005

Zheng Hongxia, Schuetz Erin, Zeevi Adriana, Zhang Jiong, McCurry Kenneth, Webber Steven, Iacono Aldo, Lamba Jatinder, Burckart Gilbert J

Abstract excerpt

The genetic polymorphisms in the ABCB1 gene, which encodes for the membrane pump, P-glycoprotein, have been previously demonstrated to have an association with tacrolimus dosing in organ transplant patients. This study associated the haplotype and genotype for ABCB1 G2677T and C3435T variants with a sequential analysis of tacrolimus blood level (ng/mL) per mg/day dosage ([L/D]) administered to 91 adult lung...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15778421
DOI: 10.1177/0091270005274507

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sequential analysis of tacrolimus dosing in adult lung transplant patients with ABCB1 haplotypes.PMID 15778421Read ↗

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