Article
Primary thrombophilia in Mexico IV: frequency of the Leiden, Cambridge, Hong Kong, Liverpool and HR2 haplotype polymorphisms in the factor V gene of a group of thrombophilic Mexican Mestizo patients.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion - 1 Jan 2000
Ruiz-Argüelles Guillermo J, Poblete-Naredo Iraís, Reyes-Núñez Virginia, Garcés-Eisele Javier, López-Martínez Briceida, Gómez-Rangel J David
Abstract excerpt
The activated protein C resistance (APCr) phenotype is found in around 40% of thrombophilic Mexican Mestizo individuals; since only very few display the factor V gene Leiden (Arg506Gln) mutation, it was considered of interest looking for other factor V gene mutations associated to thrombophilia: The HR2 haplotype, the factor V Cambridge (Arg306Thr), the factor V Hong Kong (Arg306Gly) and the FV Liverpool...
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