Article
Association of resistance to activated protein with the presence of Leiden and Cambridge Factor V mutations in Mexican patients with primary thrombophilia.
Cirugia y cirujanos - 1 Jan 2000
Zavala Hernández César, Hernández Zamora Edgar, Martínez Murillo Carlos, Arenas Sordo María de la Luz, González Orozco Ana Elena, Reyes Maldonado Elba
Abstract excerpt
BACKGROUND: Leiden and Cambridge factor V coagulation mutations and activated protein C resistance (RaPC) are alterations related with vein and artery thrombosis. In this study we aimed to determine whether RaPC is associated with the presence of Leiden and Cambridge mutation and the frequency of these mutations in the racially mestizo Mexican population. METHODS: We included 150 Mexican patients with primary...
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