Article
Neonatal immunoglobulin secretion and lymphocyte phenotype in rat small intestine lamina propria.
Pediatric research - 1 Jul 2005
Pérez-Cano Francisco J, Castellote Cristina, Marín-Gallén Silvia, Franch Angels, Castell Margarida
Abstract excerpt
We characterized the lymphocyte phenotype and the ability to produce Ig by lamina propria (LP) cells from rat ileum throughout the suckling period. In the first week after birth, <10% of LP lymphocytes were B cells, but at weaning, this figure rose to >30% as found in the adult. These B cells did not bear surface IgA (sIgA-). However, the number of sIgA+, which may correspond to B blast cells because they were...
Topics
- Animals
- Animals, Newborn
- CD3 Complex
- CD4-Positive T-Lymphocytes
- CD5 Antigens
- CD8 Antigens
- Enzyme-Linked Immunosorbent Assay
- Female
- Flow Cytometry
- Immunoglobulin A
- Immunoglobulin M
- Immunoglobulins
- Intestine, Small