Article
Spermine induces maturation of the immature intestinal immune system in neonatal mice.
Journal of pediatric gastroenterology and nutrition - 1 Sept 1997
ter Steege J C, Buurman W A, Forget P P
Abstract excerpt
BACKGROUND: In mice, immunological adaptation of the gut to microbial and nutritional antigens occurs at weaning in parallel with biochemical and morphological maturation. Because oral administration of spermine to neonatal rats has been shown to induce biochemical and morphological maturation, w...
Topics
- Aging
- Animals
- Animals, Newborn
- CD4 Antigens
- CD5 Antigens
- Epithelial Cells
- Immunity, Mucosal
- Intercellular Adhesion Molecule-1
- Intestines
- Lactase
- Lymphocytes
- Mice
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta
- Spermine
- Sucrase
- beta-Galactosidase